The unit centers on pharmacology, clinical pharmacokinetics, and therapeutic optimization in oncology and hematology. Our work spans drug monitoring, dose individualization, and safety evaluation in complex clinical settings, with strong orientation toward pediatric and adult oncology, anti-infective therapy, and pharmacometrics. The unit also provides therapeutic drug monitoring protocols, pharmacogenetic analyses, and counseling for drug-drug interactions at AOUP.
Research units
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Clinical Pharmacology & Pharmacogenetics Unit
Clinical Pharmacology & Pharmacogenetics Unit
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Research areas
Pharmacokinetics and TDM
Therapeutic drug monitoring in oncology and hematology, with dose individualization for narrow-index drugs.
Drug delivery and biomarkers
Mechanistic and translational pharmacology applied to cancer therapy and chronic diseases.
Anti-infective therapy
Antimicrobial treatment optimization and patient-specific factors influencing efficacy and tolerability.
Pediatric and adult oncology
Treatment outcomes, toxicity profiles, and innovative pharmacological approaches across age groups.
Pharmacometrics
Identification of factors influencing drug pharmacokinetics in adult and pediatric patients.
Recent publications
Team
Prof. Di Paolo
Head of unit
External affiliations
- Phase I Clinical Trial Unit, IRCCS/IRST “Dino Amadori”, Meldola
- Italian Society of Pharmacology · IATDMCT · SIBioC